The role of Interleukin 28B gene polymorphism in Turkish patients with hepatocellular carcinoma
نویسندگان
چکیده
منابع مشابه
The role of interleukin 28B gene polymorphism in Turkish patients with hepatocellular carcinoma.
BACKGROUND AND AIM Multiple risk factors lead to hepatocellular carcinoma (HCC) including viral infections, mutation and single nucleotide polymorphisms (SNPs). Interleukin 28B (IL28B) gene rs12979860 polymorphism has been shown to be associated with HCC in the different populations, but its association with HCC has not been investigated in the Turkish population. We investigated whether the rs...
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15 صفحه اولCharacterization of the Interleukin-28B Gene rs12979860 C/T Polymorphism in Turkish Chronic Hepatitis C Patients and Healthy Individuals.
BACKGROUND Host genetic factors can affect the progress of hepatitis-C virus (HCV) infection. Interleukin-28B (IL28B) single nucleotide polymorphisms may play an important role in the clearance of HCV spontaneously or with treatment. AIMS The aim of our study was to evaluate the rate of IL28B genotypes in patients with Chronic Hepatitis-C (CHC) and healthy control subjects and to examine the ...
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متن کاملAssociation of interleukin-28B genotype and hepatocellular carcinoma recurrence in patients with chronic hepatitis C.
PURPOSE Several single-nucleotide polymorphisms (SNP) in the interleukin-28B (IL-28B) locus have recently been shown to be associated with antiviral treatment efficacy for chronic hepatitis C (CHC). However, such an association with hepatocellular carcinoma (HCC) is unkno3 we investigated the association between the IL-28B genotype and the biology and clinical outcome of patients with HCC recei...
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ژورنال
عنوان ژورنال: Annals of Hepatology
سال: 2014
ISSN: 1665-2681
DOI: 10.1016/s1665-2681(19)30981-0